Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976883 | 0.77 | KDM4E (0.52) | SMN1; SMN2GLAALDH1A1MAPK1HIF1A | |
| SCHEMBL2921484 | 0.73 | SMN1; SMN2 (0.67) | SMN1; SMN2GLAALDH1A1PAOXMEN1 | |
| SCHEMBL8280157 | 0.70 | TDP1 (0.58) | SMN1; SMN2TDP1ALDH1A1KMT2ATSHR | |
| SCHEMBL27572400 | 0.70 | ATM (0.51) | SMN1; SMN2GLATDP1ALDH1A1GAA | |
| SCHEMBL9925862 | 0.70 | SMN1; SMN2 (0.54) | SMN1; SMN2GLAALDH1A1PAOXGAA | |
| SCHEMBL14079974 | 0.70 | MEN1 (0.44) | SMN1; SMN2GLATDP1ALDH1A1PAOX | |
| SCHEMBL13793568 | 0.69 | TDP1 (0.49) | SMN1; SMN2GLATDP1ALDH1A1PAOX | |
| SCHEMBL13368566 | 0.69 | TDP1 (0.69) | TDP1GAAKDM4EKMT2ATSHR | |
| SCHEMBL674062 | 0.69 | ALDH1A1 (0.52) | SMN1; SMN2GLAALDH1A1MAPK1KDM4E | |
| SCHEMBL6044315 | 0.69 | GLA (0.47) | SMN1; SMN2GLAALDH1A1MAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |