Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963380 | 0.89 | GAA (0.53) | KDM4EGLAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7977217 | 0.77 | SMN1; SMN2 (0.45) | KDM4EGLAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL5347793 | 0.77 | KDM4E (0.47) | KDM4EGLAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL951890 | 0.74 | GLA (0.64) | KDM4EGLAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL4332122 | 0.73 | KDM4E (0.52) | KDM4EGLAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL15932891 | 0.73 | LMNA (0.46) | KDM4EGLAGAAALDH1A1SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL11367143 | 0.73 | LMNA (0.55) | KDM4EGLAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL10501656 | 0.73 | KEAP1 (0.52) | KDM4EGLAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL6044315 | 0.73 | GLA (0.47) | KDM4EGLAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL1358701 | 0.72 | KDM4E (0.61) | KDM4EGLAGAAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288380-B2 | Thiophenediamine derivative having urea structure | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2012-10-16 | — | — | US | disclosed |
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |
| EP-0431568-B1 | Method for processing a silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 1996-10-16 | — | — | EP | disclosed |
| US-5415983-A | Method for processing a silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1995-05-16 | — | — | US | disclosed |
| EP-0283041-B1 | DIRECT POSITIVE SILVER HALIDE PHOTOSENSITIVE MATERIAL AND METHOD FOR FORMING DIRECT POSITIVE IMAGE | FUJI PHOTO FILM CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |
| US-5037726-A | Imagewise exposure of photographic light sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0431568-A1 | Method for processing a silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-06-12 | — | — | EP | disclosed |
| US-4952483-A | NOVEL HYDRAZINE NUCLEATING AGENTS AND ACCELERATORS | FUJI PHOTO FILM CO., LTD. (JP) | 1990-08-28 | — | — | US | disclosed |
| US-4871653-A | DEVELOPING IN PRESENCE OF MERCAPTO POLYAZAINDENE PROMOTERS AND NUCLEATING QUATERNARY OR HYDRAZIDE-TYPE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-03 | — | — | US | disclosed |
| EP-0283041-A1 | Direct positive silver halide photosensitive material and method for forming direct positive image | FUJI PHOTO FILM CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |