Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977230 | 0.82 | MAPT (0.42) | POLBSIGMAR1MAPTGAAHPGD | |
| SCHEMBL6692894 | 0.76 | FFAR1 (0.43) | SIGMAR1MAPTGAAHPGDRAB9A | |
| SCHEMBL5213853 | 0.73 | HDAC3 (0.47) | POLBMAPTALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL28904890 | 0.73 | MAPT (0.46) | SIGMAR1MAPTGAAHPGDRAB9A | |
| SCHEMBL2015299 | 0.72 | MAPT (0.44) | SIGMAR1MAPTGAAHPGDRAB9A | |
| SCHEMBL3732806 | 0.72 | MAPT (0.48) | SIGMAR1MAPTGAAHPGDRAB9A | |
| SCHEMBL11079885 | 0.71 | HDAC8 (0.46) | POLBMAPTHPGDRAB9AALDH1A1 | |
| SCHEMBL30826536 | 0.71 | PRSS1 (0.49) | MAPTGAAHPGDRAB9AALDH1A1 | |
| SCHEMBL11451181 | 0.71 | POLB (0.53) | POLBGAARAB9AHSD17B10CYP2C9 | |
| Hydrochloric Acid SCHEMBL17710416 | 0.70 | MAPT (0.46) | SIGMAR1MAPTGAAHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |