Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977228 | 0.82 | POLB (0.41) | MAPTGAAPOLBHPGDRAB9A | |
| SCHEMBL28904890 | 0.80 | MAPT (0.46) | MAPTGAAGFERMAPK8KMT2A | |
| SCHEMBL6692894 | 0.76 | FFAR1 (0.43) | MAPTGAAHPGDRAB9ANAPRT | |
| SCHEMBL28904881 | 0.74 | MAPT (0.39) | MAPTGAAGFERMAPK8KMT2A | |
| SCHEMBL2015299 | 0.72 | MAPT (0.44) | MAPTGAAKMT2AHPGDRAB9A | |
| SCHEMBL6702352 | 0.72 | TAAR1 (0.46) | MAPTKMT2AHSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL5091146 | 0.72 | PKM (0.38) | MAPTGAAMAPK8HPGDRAB9A | |
| SCHEMBL3732806 | 0.72 | MAPT (0.48) | MAPTGAAMAPK8KMT2AHPGD | |
| SCHEMBL30826536 | 0.71 | PRSS1 (0.49) | MAPTGAAKMT2AHPGDRAB9A | |
| SCHEMBL11079885 | 0.71 | HDAC8 (0.46) | MAPTPOLBKMT2AHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |