SCHEMBL6692894

SCHEMBL6692894

CC(C)(CNc1ccccc1)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.43
LMNA P02545 1/20 0.42
MAPT P10636 2/20 0.42
GAA P10253 1/20 0.42
HPGD P15428 1/20 0.42
RAB9A P51151 1/20 0.42
NAPRT Q6XQN6 1/20 0.42
HSD17B10 Q99714 1/20 0.42
PRSS1 P07477 1/20 0.41
CTSG P08311 1/20 0.41
CTRB1 P17538 1/20 0.41
CMA1 P23946 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
PDK1 Q15118 2/20 0.41
PDK2 Q15119 2/20 0.41
PDK3 Q15120 2/20 0.41
PDK4 Q16654 2/20 0.41
SIGMAR1 Q99720 1/20 0.41
HIF1A Q16665 4/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28904890 0.85 MAPT (0.46) FFAR1MAPTGAAHPGDRAB9A
SCHEMBL11079885 0.83 HDAC8 (0.46) FFAR1MAPTHPGDRAB9APRSS1
SCHEMBL30826536 0.83 PRSS1 (0.49) FFAR1LMNAMAPTGAAHPGD
SCHEMBL18109250 0.81 LMNA (0.34) FFAR1LMNAMAPTGAAHPGD
SCHEMBL5401394 0.80 PRSS1 (0.46) FFAR1LMNAMAPTGAAHPGD
SCHEMBL2015299 0.77 MAPT (0.44) FFAR1MAPTGAAHPGDRAB9A
SCHEMBL5091146 0.77 PKM (0.38) FFAR1LMNAMAPTGAAHPGD
SCHEMBL6780544 0.77 FFAR1 (0.57) FFAR1CA1CA2HIF1A
SCHEMBL3732806 0.76 MAPT (0.48) MAPTGAAHPGDRAB9AHSD17B10
SCHEMBL7977228 0.76 POLB (0.41) FFAR1LMNAMAPTGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004109398-A1 PHOTOGRAPHIC ELEMENT CONTAINING IMPROVED COUPLER MOIETY EASTMAN KODAK COMPANY (US) 2004-12-16 WO disclosed
US-6780573-B1 ADEQUATE DIFFUSION RESISTANCE WITHOUT BALLAST; MINIMIZED SPEED LOSS; GREATER INTERIMAGE; EFFICIENT REMOVAL EASTMAN KODAK COMPANY 2004-08-24 US disclosed