Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 5/20 | 0.41 |
| ▸ | NOS1 | P29475 | 3/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | ARG1 | P05089 | 1/20 | 0.38 |
| ▸ | ARG2 | P78540 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5511756 | 0.87 | ARG1 (0.53) | TSHRNOS2NOS1NOS3ARG1 | |
| SCHEMBL8470091 | 0.87 | ARG1 (0.53) | TSHRNOS2NOS1NOS3ARG1 | |
| SCHEMBL2757814 | 0.87 | ARG1 (0.53) | TSHRNOS2NOS1NOS3ARG1 | |
| Hydrochloric Acid SCHEMBL5514288 | 0.85 | ARG1 (0.51) | TSHRNOS2NOS1NOS3ARG1 | |
| Hydrochloric Acid SCHEMBL5514291 | 0.85 | ARG1 (0.51) | TSHRNOS2NOS1NOS3ARG1 | |
| Hydrochloric Acid SCHEMBL8469599 | 0.85 | ARG1 (0.51) | TSHRNOS2NOS1NOS3ARG1 | |
| SCHEMBL6149856 | 0.84 | TSHR (0.39) | TSHRNOS2NOS1NOS3ARG1 | |
| Gw-274150 SCHEMBL1690580 | 0.75 | BHMT (0.54) | TSHRNOS2NOS1NOS3 | |
| Gw-274150 SCHEMBL120694 | 0.75 | BHMT (0.54) | TSHRNOS2NOS1NOS3 | |
| Gw-274150 SCHEMBL120693 | 0.75 | BHMT (0.54) | TSHRNOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001005748-A1 | OLIGOMERIC AMINO ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | MONSANTO COMPANY (US) | 2001-01-25 | — | — | WO | disclosed |