Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991972 | 0.94 | GAA (0.45) | GAARAB9ATP53NPC1LMNA | |
| SCHEMBL7991191 | 0.90 | GAA (0.42) | GAARAB9ATP53NPC1LMNA | |
| SCHEMBL7987565 | 0.83 | L3MBTL1 (0.55) | NPC1LMNAMAPTL3MBTL1HRH3 | |
| SCHEMBL647792 | 0.83 | FURIN (0.43) | GAARAB9ATP53NPC1LMNA | |
| SCHEMBL647793 | 0.83 | FURIN (0.43) | GAARAB9ATP53NPC1LMNA | |
| SCHEMBL4384958 | 0.82 | KDM4E (0.38) | GAARAB9ATP53NPC1LMNA | |
| SCHEMBL4384962 | 0.82 | KDM4E (0.38) | GAARAB9ATP53NPC1LMNA | |
| SCHEMBL4390061 | 0.79 | CYP1A2 (0.40) | GAARAB9ATP53NPC1LMNA | |
| SCHEMBL4390064 | 0.79 | CYP1A2 (0.40) | GAARAB9ATP53NPC1LMNA | |
| SCHEMBL7990745 | 0.79 | HRH2 (0.57) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |