Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | HRH2 | P25021 | 5/20 | 0.48 |
| ▸ | HRH1 | P35367 | 5/20 | 0.48 |
| ▸ | THRB | P10828 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990745 | 0.93 | HRH2 (0.57) | L3MBTL1HRH2HRH1THRBTHRA | |
| SCHEMBL7987723 | 0.92 | HRH2 (0.56) | L3MBTL1HRH2HRH1THRBTHRA | |
| SCHEMBL7977335 | 0.90 | SMN1; SMN2 (0.51) | L3MBTL1HRH2HRH1HRH3MAPT | |
| SCHEMBL7994845 | 0.88 | L3MBTL1 (0.48) | L3MBTL1HRH2HRH1HRH3MAPT | |
| SCHEMBL7977269 | 0.84 | CES2 (0.45) | L3MBTL1MMP1HRH3 | |
| SCHEMBL4376187 | 0.84 | L3MBTL1 (0.59) | L3MBTL1HRH2HRH1ALDH1A1LMNA | |
| SCHEMBL7987591 | 0.84 | HRH3 (0.42) | L3MBTL1MMP1HRH3MAPT | |
| SCHEMBL4381007 | 0.83 | SMN1; SMN2 (0.52) | L3MBTL1HRH2HRH1HRH3MAPT | |
| SCHEMBL7977277 | 0.83 | GAA (0.43) | L3MBTL1LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4383468 | 0.83 | KDM4E (0.44) | L3MBTL1ALDH1A1LMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |