Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978046 | 0.91 | RAB9A (0.48) | RAB9ANPC1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL7989176 | 0.87 | NPC1 (0.55) | RAB9ANPC1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL7991736 | 0.86 | RAB9A (0.54) | RAB9ANPC1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL7977681 | 0.86 | RAB9A (0.54) | RAB9ANPC1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL7992115 | 0.81 | RAB9A (0.51) | RAB9ANPC1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL7978151 | 0.81 | RAB9A (0.51) | RAB9ANPC1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL7995308 | 0.81 | NPC1 (0.48) | RAB9ANPC1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL7991835 | 0.81 | RAB9A (0.50) | RAB9ANPC1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL7988275 | 0.79 | MAPT (0.48) | RAB9ANPC1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL7988455 | 0.79 | BACE1 (0.51) | RAB9ANPC1KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |