Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | LATS1 | O95835 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977462 | 0.84 | GAA (0.35) | HDAC1GAACYP3A4CYP11B1CYP11B2 | |
| SCHEMBL24342227 | 0.81 | CYP3A4 (0.36) | GAACYP3A4CYP11B1CYP11B2HRH4 | |
| SCHEMBL20011113 | 0.74 | CDC7 (0.39) | CYP3A4CYP11B1CYP11B2ADORA3ADORA2A | |
| SCHEMBL4013751 | 0.72 | BRPF1 (0.50) | HDAC1GAAADORA3CYP2D6MAPT | |
| SCHEMBL30791421 | 0.72 | HTR2A (0.37) | GAALATS1CHRNB2CHRNA4 | |
| SCHEMBL7679422 | 0.71 | CYP3A4 (0.38) | GAACYP3A4CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL7920705 | 0.69 | HDAC1 (0.33) | HDAC1CYP1A2CYP2A6 | |
| SCHEMBL8561528 | 0.68 | GRIA2 (0.50) | CYP3A4HRH4 | |
| SCHEMBL261618 | 0.68 | CYP3A4 (0.40) | GAACYP3A4CYP11B1CYP11B2MAPT | |
| SCHEMBL16724490 | 0.68 | GAA (0.48) | GAACYP3A4ADORA3ADORA2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9929361-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2018-03-27 | — | — | US | disclosed |
| WO-2009147476-A1 | NOVEL PDE INHIBITORS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | MATRIX LABORATORIES LTD. (IN) | 2009-12-10 | — | — | WO | disclosed |