Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.76 |
| ▸ | GAA | P10253 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.67 |
| ▸ | TRIM33 | Q9UPN9 | 3/20 | 0.67 |
| ▸ | GFER | P55789 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | BRD4 | O60885 | 1/20 | 0.65 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.63 |
| ▸ | PIM1 | P11309 | 1/20 | 0.63 |
| ▸ | GSK3B | P49841 | 1/20 | 0.63 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.63 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.60 |
| ▸ | SALL4 | Q9UJQ4 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975156 | 0.91 | ADORA1 (0.81) | ADORA1GAAALDH1A1ALOX5TRIM33 | |
| SCHEMBL2986663 | 0.90 | ADORA1 (0.79) | ADORA1GAAALDH1A1ALOX5TRIM33 | |
| SCHEMBL14421385 | 0.87 | PABPC1 (0.71) | ADORA1GAAALDH1A1ALOX5TRIM33 | |
| SCHEMBL15152601 | 0.86 | ADORA1 (0.78) | ADORA1GAAALDH1A1ALOX5TRIM33 | |
| SCHEMBL1965852 | 0.86 | ADORA1 (0.78) | ADORA1GAAALDH1A1ALOX5TRIM33 | |
| SCHEMBL1967978 | 0.86 | ADORA1 (0.78) | ADORA1GAAALDH1A1ALOX5TRIM33 | |
| SCHEMBL2977991 | 0.86 | ADORA1 (1.00) | ADORA1GAAALDH1A1ALOX5TRIM33 | |
| SCHEMBL1965930 | 0.86 | ADORA1 (0.78) | ADORA1GAAALDH1A1ALOX5TRIM33 | |
| SCHEMBL1966523 | 0.86 | ADORA1 (0.73) | ADORA1GAAALDH1A1ALOX5TRIM33 | |
| SCHEMBL1965379 | 0.85 | ADORA1 (0.76) | ADORA1GAAALDH1A1ALOX5TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001027119-A2 | SUBSTANCE LIBRARY CONTAINING BICYCLIC IMIDAZO-5-YL-AMINES AND/OR BICYCLIC IMIDAZO-3-YL-AMINES | Grünenthal GmbH (DE) | 2001-04-19 | — | — | WO | claimed |
| WO-2001027119-A2 | SUBSTANCE LIBRARY CONTAINING BICYCLIC IMIDAZO-5-YL-AMINES AND/OR BICYCLIC IMIDAZO-3-YL-AMINES | Grünenthal GmbH (DE) | 2001-04-19 | — | — | WO | disclosed |