Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 12/20 | 0.49 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977558 | 0.90 | HSD11B1 (0.49) | HSD11B1PLA2G7NPC1ALDH1A1LMNA | |
| SCHEMBL7982107 | 0.87 | HSD11B1 (0.52) | HSD11B1HSD11B2 | |
| SCHEMBL7984073 | 0.84 | HSD11B1 (0.44) | HSD11B1LMNA | |
| SCHEMBL12671007 | 0.84 | HSD11B1 (0.46) | HSD11B1NPC1ALDH1A1LMNARAB9A | |
| SCHEMBL7977548 | 0.82 | HSD11B1 (0.47) | HSD11B1NPC1ALDH1A1LMNARAB9A | |
| SCHEMBL7984122 | 0.78 | HSD11B1 (0.47) | HSD11B1NPC1ALDH1A1LMNARAB9A | |
| SCHEMBL7979284 | 0.77 | HSD11B1 (0.45) | HSD11B1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL12671008 | 0.77 | HSD11B1 (0.46) | HSD11B1ALDH1A1 | |
| SCHEMBL7981679 | 0.75 | HSD11B1 (0.53) | HSD11B1 | |
| SCHEMBL7979418 | 0.75 | HSD11B1 (0.50) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |