SCHEMBL7977548 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	HSD11B1	P28845	13/20	0.47

▸	RORC	P51449	1/20	0.39

▸	LMNA	P02545	2/20	0.38

▸	NPC1	O15118	1/20	0.38

▸	ALDH1A1	P00352	1/20	0.38

▸	RAB9A	P51151	1/20	0.38

▸	SMN1; SMN2	Q16637	1/20	0.38

▸	MAPT	P10636	1/20	0.35

▸	TSHR	P16473	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7984122	0.91	HSD11B1 (0.47)	HSD11B1LMNANPC1ALDH1A1RAB9A
SCHEMBL7987984	0.88	HSD11B1 (0.50)	HSD11B1
SCHEMBL7967520	0.85	HSD11B1 (0.42)	HSD11B1RORCLMNAMAPTTSHR
SCHEMBL12671009	0.84	HSD11B1 (0.44)	HSD11B1RORC
SCHEMBL7977555	0.82	HSD11B1 (0.49)	HSD11B1LMNANPC1ALDH1A1RAB9A
SCHEMBL7988091	0.78	HSD11B1 (0.43)	HSD11B1RORCLMNAMAPTTSHR
SCHEMBL12671016	0.78	HSD11B1 (0.45)	HSD11B1
SCHEMBL7977558	0.77	HSD11B1 (0.49)	HSD11B1LMNANPC1ALDH1A1RAB9A
SCHEMBL7985076	0.76	HSD11B1 (0.51)	HSD11B1RAB9ASMN1; SMN2
SCHEMBL7982228	0.76	HSD11B1 (0.51)	HSD11B1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2010001946-A1	TRIAZOLE DERIVATIVE OR SALT THEREOF	アステラス製薬株式会社 (JP)	2010-01-07	—	—	WO	disclosed