Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23748685 | 0.89 | KDM4E (0.53) | KDM4EALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL28478929 | 0.87 | ALDH1A1 (0.66) | KDM4EALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL1662789 | 0.85 | TSHR (0.63) | KDM4EALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL31437079 | 0.84 | MAPT (0.49) | KDM4EALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL24571900 | 0.84 | MAPT (0.49) | KDM4EALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL31033384 | 0.82 | CHEK1 (0.51) | KDM4EALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL5838452 | 0.82 | CHEK1 (0.51) | KDM4EALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL385973 | 0.82 | HSP90AA1 (0.59) | KDM4EALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL1050558 | 0.81 | ALDH1A1 (0.49) | KDM4EALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL11252714 | 0.79 | KDM4E (0.43) | KDM4EALDH1A1LMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |