Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24571900 | 1.00 | MAPT (0.49) | MAPTHSP90AA1HTTNPSR1KDM4E | |
| SCHEMBL6280141 | 0.85 | HSP90AA1 (0.59) | MAPTHSP90AA1HTTNPSR1KDM4E | |
| SCHEMBL31051133 | 0.85 | CNR2 (0.44) | HTTKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL11418287 | 0.84 | ALDH1A1 (0.51) | HTTKDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL7977563 | 0.84 | KDM4E (0.56) | MAPTHSP90AA1HTTNPSR1KDM4E | |
| SCHEMBL23748685 | 0.84 | KDM4E (0.53) | MAPTHSP90AA1HTTNPSR1KDM4E | |
| SCHEMBL31033384 | 0.83 | CHEK1 (0.51) | MAPTHSP90AA1HTTNPSR1KDM4E | |
| SCHEMBL5838452 | 0.83 | CHEK1 (0.51) | MAPTHSP90AA1HTTNPSR1KDM4E | |
| SCHEMBL25244052 | 0.82 | MAPT (0.48) | MAPTHSP90AA1HTTNPSR1KDM4E | |
| SCHEMBL19709550 | 0.81 | MAPT (0.47) | MAPTHSP90AA1HTTNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119630644-A | Bifunctional compounds containing pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-119630651-A | Bifunctional compounds containing substituted pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-03-14 | — | — | CN | disclosed |