Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
| ▸ | HK1 | P19367 | 1/20 | 0.49 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988543 | 0.93 | KMT2A (0.48) | MAPK1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL7992106 | 0.91 | RAB9A (0.50) | MAPK1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL7989229 | 0.91 | MEN1 (0.56) | MAPK1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL7989511 | 0.89 | MEN1 (0.47) | MAPK1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL7991821 | 0.89 | RAB9A (0.45) | MAPK1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL7988925 | 0.89 | MAPK1 (0.50) | MAPK1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL7989571 | 0.89 | MAPK1 (0.56) | MAPK1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL7995546 | 0.88 | MAPK1 (0.55) | MAPK1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL7990001 | 0.87 | MEN1 (0.52) | MAPK1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL7991985 | 0.86 | SMN1; SMN2 (0.46) | MAPK1L3MBTL1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | claimed |
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |