Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | COMT | P21964 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989576 | 0.91 | RAB9A (0.46) | SMN1; SMN2RAB9ANPC1L3MBTL1MAPT | |
| SCHEMBL7977897 | 0.89 | RAB9A (0.46) | SMN1; SMN2RAB9ANPC1L3MBTL1COMT | |
| SCHEMBL7995060 | 0.88 | COMT (0.47) | SMN1; SMN2RAB9ANPC1L3MBTL1COMT | |
| SCHEMBL7977664 | 0.86 | MAPK1 (0.55) | SMN1; SMN2RAB9ANPC1L3MBTL1MAPT | |
| SCHEMBL7989018 | 0.85 | MAPT (0.47) | SMN1; SMN2RAB9ANPC1L3MBTL1MAPT | |
| SCHEMBL7988044 | 0.83 | NPC1 (0.47) | SMN1; SMN2RAB9ANPC1L3MBTL1MAPT | |
| SCHEMBL7978021 | 0.83 | SMN1; SMN2 (0.43) | SMN1; SMN2RAB9ANPC1L3MBTL1COMT | |
| SCHEMBL7992142 | 0.83 | RAB9A (0.47) | SMN1; SMN2RAB9ANPC1L3MBTL1MAPT | |
| SCHEMBL7992115 | 0.81 | RAB9A (0.51) | SMN1; SMN2RAB9ANPC1L3MBTL1COMT | |
| SCHEMBL7988275 | 0.80 | MAPT (0.48) | SMN1; SMN2RAB9ANPC1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |