Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992024 | 0.93 | AR (0.58) | ARGAARAB9AMAPTMEN1 | |
| SCHEMBL7988102 | 0.92 | MAPT (0.54) | ARPTPN11GAARAB9AMAPT | |
| SCHEMBL7988441 | 0.90 | AR (0.55) | ARGAARAB9AMAPTMEN1 | |
| SCHEMBL28914603 | 0.89 | AR (0.54) | ARGAARAB9AMAPTMEN1 | |
| SCHEMBL7991748 | 0.89 | CHEK2 (0.50) | GAARAB9AMAPTPTGS2CHEK2 | |
| SCHEMBL7989862 | 0.89 | AR (0.54) | ARGAARAB9AMAPTMEN1 | |
| SCHEMBL7988260 | 0.89 | MAPT (0.51) | ARGAARAB9AMAPTMEN1 | |
| SCHEMBL7991878 | 0.89 | AR (0.49) | ARPTPN11GAARAB9AMAPT | |
| SCHEMBL7992254 | 0.88 | MAPT (0.54) | ARGAARAB9AMAPTMEN1 | |
| SCHEMBL7995187 | 0.88 | AR (0.53) | ARPTPN11GAARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |