Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | STAT1 | P42224 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.54 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 2/20 | 0.52 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.50 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992024 | 0.93 | AR (0.58) | MAPTGAAHTTMEN1KMT2A | |
| SCHEMBL7977720 | 0.92 | AR (0.52) | MAPTGAASMN1; SMN2HTTMEN1 | |
| SCHEMBL7988441 | 0.90 | AR (0.55) | MAPTGAASMN1; SMN2HTTMEN1 | |
| SCHEMBL7989862 | 0.89 | AR (0.54) | MAPTGAAHTTMEN1KMT2A | |
| SCHEMBL28914603 | 0.89 | AR (0.54) | MAPTGAAHTTMEN1KMT2A | |
| SCHEMBL7995168 | 0.89 | MAPT (0.51) | MAPTGAASMN1; SMN2HTTMEN1 | |
| SCHEMBL7988461 | 0.89 | F2 (0.50) | MAPTGAASMN1; SMN2HTTMEN1 | |
| SCHEMBL7991878 | 0.89 | AR (0.49) | MAPTGAASMN1; SMN2HTTMEN1 | |
| SCHEMBL7992254 | 0.88 | MAPT (0.54) | MAPTGAAHTTMEN1KMT2A | |
| SCHEMBL7995187 | 0.88 | AR (0.53) | MAPTGAASMN1; SMN2HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |