Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.54 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992024 | 0.94 | AR (0.58) | MAPTRAB9AMEN1KMT2AMAPK14 | |
| SCHEMBL7988441 | 0.91 | AR (0.55) | MAPTRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL7989862 | 0.90 | AR (0.54) | MAPTRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL28914603 | 0.90 | AR (0.54) | MAPTRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL7995187 | 0.89 | AR (0.53) | MAPTRAB9AMEN1KMT2AALOX5 | |
| SCHEMBL7991863 | 0.89 | MAPT (0.52) | MAPTRAB9AMEN1KMT2AALOX5 | |
| SCHEMBL7991922 | 0.89 | AR (0.50) | MAPTRAB9AMEN1KMT2AALOX5 | |
| SCHEMBL7977720 | 0.88 | AR (0.52) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL7988102 | 0.88 | MAPT (0.54) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL7977722 | 0.87 | NPBWR1 (0.53) | MAPTRAB9AMEN1KMT2AMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |