Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | DUT | P33316 | 2/20 | 0.31 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.31 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557227 | 0.73 | CRBN (0.56) | CRBNDDB1 | |
| SCHEMBL2709043 | 0.73 | CRBN (0.56) | CRBNDDB1DUT | |
| SCHEMBL6406005 | 0.73 | CRBN (0.56) | CRBNDDB1PKMDUT | |
| SCHEMBL8018395 | 0.73 | CRBN (0.56) | CRBNDDB1 | |
| SCHEMBL28813571 | 0.71 | MAPT (0.46) | CRBNDDB1 | |
| SCHEMBL7457109 | 0.69 | CRBN (0.51) | CRBNDDB1MCL1 | |
| SCHEMBL8936411 | 0.68 | CRBN (0.50) | CRBNDDB1DUT | |
| SCHEMBL8013276 | 0.68 | CRBN (0.50) | CRBNDDB1DUT | |
| SCHEMBL1530734 | 0.67 | CRBN (1.00) | CRBNDDB1DUT | |
| SCHEMBL7918717 | 0.67 | CRBN (0.49) | CRBNDDB1DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030782-A2 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-05-03 | — | — | WO | disclosed |