Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.56 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | HCAR1 | Q9BXC0 | 6/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2709043 | 0.78 | CRBN (0.56) | CRBNDDB1KDM4EGAAALDH1A1 | |
| SCHEMBL6406005 | 0.78 | CRBN (0.56) | CRBNDDB1HCAR1 | |
| SCHEMBL8018395 | 0.78 | CRBN (0.56) | CRBNDDB1KDM4EALDH1A1HCAR1 | |
| SCHEMBL8936411 | 0.76 | CRBN (0.50) | CRBNDDB1 | |
| SCHEMBL7457109 | 0.74 | CRBN (0.51) | CRBNDDB1KDM4EGAA | |
| SCHEMBL7977829 | 0.73 | CRBN (0.50) | CRBNDDB1 | |
| SCHEMBL8013276 | 0.73 | CRBN (0.50) | CRBNDDB1HCAR1 | |
| SCHEMBL7805547 | 0.73 | CA12 (0.54) | BRD4KDM4EPOLBGAAALDH1A1 | |
| SCHEMBL1530734 | 0.72 | CRBN (1.00) | CRBNDDB1GAAHCAR1 | |
| SCHEMBL6174758 | 0.72 | BRD4 (0.46) | BRD4KDM4EPOLBGAAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021417-B1 | SUBSTITUTED PHENYLURACILS | BAYER CROPSCIENCE AG (DE) | 2004-03-10 | — | — | EP | claimed |
| US-6362337-B1 | ACYLATING A HYDROXYPHENYLURACIL COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-26 | — | — | US | claimed |
| US-6362337-B1 | ACYLATING A HYDROXYPHENYLURACIL COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-26 | — | — | US | disclosed |
| US-6277789-B1 | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-21 | — | — | US | disclosed |