Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.50 |
| ▸ | DUT | P33316 | 12/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936411 | 0.84 | CRBN (0.50) | CRBNDDB1DUTCA2CA7 | |
| SCHEMBL8018395 | 0.76 | CRBN (0.56) | CRBNDDB1HCAR1 | |
| SCHEMBL6406005 | 0.73 | CRBN (0.56) | CRBNDDB1DUTHCAR1 | |
| SCHEMBL2709043 | 0.73 | CRBN (0.56) | CRBNDDB1DUTHCAR1 | |
| SCHEMBL25565848 | 0.73 | CRBN (0.56) | CRBNDDB1HCAR1 | |
| SCHEMBL6557227 | 0.73 | CRBN (0.56) | CRBNDDB1HCAR1 | |
| SCHEMBL7457109 | 0.69 | CRBN (0.51) | CRBNDDB1CA2 | |
| SCHEMBL7977829 | 0.68 | CRBN (0.50) | CRBNDDB1DUT | |
| SCHEMBL1530734 | 0.67 | CRBN (1.00) | CRBNDDB1DUTHCAR1 | |
| SCHEMBL11392065 | 0.67 | TLR9 (0.59) | CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107252-A | 1-((3-AMINOSULFONYL,4-CYANO,6-SUBSTITUTED PHENYL)-),3,4,5-SUBSTITUTED-1,2,3,6-TETRAHYDROPYRIMIDIN-2,6-DIONE COMPOUNDS; HERBICIDAL ACTIVITY AND AT THE SAME TIME COMPATIBILITY WITH CROP PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-08-22 | — | — | US | claimed |
| US-6107252-A | 1-((3-AMINOSULFONYL,4-CYANO,6-SUBSTITUTED PHENYL)-),3,4,5-SUBSTITUTED-1,2,3,6-TETRAHYDROPYRIMIDIN-2,6-DIONE COMPOUNDS; HERBICIDAL ACTIVITY AND AT THE SAME TIME COMPATIBILITY WITH CROP PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-08-22 | — | — | US | disclosed |
| US-6074989-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-06-13 | — | — | US | disclosed |