Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978038 | 1.00 | ALDH1A1 (0.40) | ALDH1A1HTTKDM4ELMNAKDM4A | |
| SCHEMBL6576752 | 0.86 | KDM4E (0.47) | ALDH1A1HTTKDM4ELMNATSHR | |
| SCHEMBL7978047 | 0.83 | ALDH1A1 (0.36) | ALDH1A1HTTKDM4ELMNATSHR | |
| SCHEMBL7964612 | 0.78 | ALDH1A1 (0.44) | ALDH1A1HTTKDM4ELMNAHPGD | |
| SCHEMBL7978004 | 0.77 | KDM4E (0.44) | ALDH1A1KDM4ETSHRHPGDHSD17B10 | |
| SCHEMBL27489938 | 0.76 | TSHR (0.56) | ALDH1A1KDM4ELMNATSHRHPGD | |
| SCHEMBL7964550 | 0.74 | TP53 (0.44) | ALDH1A1KDM4ELMNATSHRHPGD | |
| SCHEMBL6582186 | 0.72 | ALDH1A1 (0.47) | ALDH1A1HTTKDM4ELMNATSHR | |
| SCHEMBL6277838 | 0.71 | KDM4E (0.41) | ALDH1A1KDM4EHPGDHSD17B10CNR2 | |
| SCHEMBL6277841 | 0.71 | KDM4E (0.41) | ALDH1A1KDM4EHPGDHSD17B10CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |