Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576752 | 0.86 | KDM4E (0.47) | TP53LMNAHPGDHSD17B10KDM4E | |
| SCHEMBL6579485 | 0.84 | KDM4E (0.42) | TP53LMNAHPGDHSD17B10ALOX15 | |
| SCHEMBL7978004 | 0.82 | KDM4E (0.44) | HPGDHSD17B10KDM4EALDH1A1TSHR | |
| SCHEMBL7978047 | 0.82 | ALDH1A1 (0.36) | LMNAHPGDHSD17B10KDM4EALDH1A1 | |
| SCHEMBL7980772 | 0.79 | HIF1A (0.43) | LMNAHPGDHSD17B10KDM4EALDH1A1 | |
| SCHEMBL17530492 | 0.74 | MAPT (0.48) | LMNAHPGDHSD17B10ALOX15KDM4E | |
| SCHEMBL7975932 | 0.74 | ALOX5 (0.42) | HPGDHSD17B10ALOX15KDM4EALDH1A1 | |
| SCHEMBL7978038 | 0.74 | ALDH1A1 (0.40) | TP53LMNAHPGDHSD17B10KDM4E | |
| SCHEMBL7978035 | 0.74 | ALDH1A1 (0.40) | TP53LMNAHPGDHSD17B10KDM4E | |
| SCHEMBL7964612 | 0.74 | ALDH1A1 (0.44) | LMNAHPGDHSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |