SCHEMBL7978066

SCHEMBL7978066

Cc1ccc(S(=O)(=O)N2CCC[C@@H]2CC(=O)O)cc1

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.53
PAX8 Q06710 1/20 0.53
GAA P10253 1/20 0.53
HPGD P15428 1/20 0.53
FFAR1 O14842 1/20 0.52
FKBP1A P62942 1/20 0.52
L3MBTL1 Q9Y468 3/20 0.50
PSEN1 P49768 1/20 0.50
PSEN2 P49810 1/20 0.50
APH1B Q8WW43 1/20 0.50
NCSTN Q92542 1/20 0.50
APH1A Q96BI3 1/20 0.50
PSENEN Q9NZ42 1/20 0.50
MAPK1 P28482 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7968454 1.00 RAB9A (0.53) RAB9APAX8GAAHPGDFFAR1
SCHEMBL7968450 1.00 RAB9A (0.53) RAB9APAX8GAAHPGDFFAR1
SCHEMBL11113764 0.92 NPSR1 (0.50) RAB9APAX8GAAHPGDFFAR1
SCHEMBL8051860 0.88 RAB9A (0.53) RAB9APAX8GAAHPGDFKBP1A
SCHEMBL5885959 0.85 BRD4 (0.57) RAB9APAX8GAAHPGDFKBP1A
SCHEMBL5885963 0.85 BRD4 (0.57) RAB9APAX8GAAHPGDFKBP1A
SCHEMBL6302770 0.85 BRD4 (0.57) RAB9APAX8GAAHPGDFKBP1A
SCHEMBL8693171 0.83 PSEN1 (0.52) RAB9AFKBP1APSEN1PSEN2APH1B
SCHEMBL19000604 0.83 PSEN1 (0.70) RAB9APAX8GAAHPGDPSEN1
SCHEMBL12169293 0.83 PSEN1 (0.70) RAB9APAX8GAAHPGDPSEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6225306-B1 PYRROLO(1,2A)QUINOXALINES WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) 2001-05-01 US disclosed
EP-0987266-A1 BIPHENYL DERIVATIVES AND MEDICINAL COMPOSITIONS Wakamoto Pharmaceutical Co., Ltd. (JP) 2000-03-22 EP disclosed