Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 7/20 | 0.38 |
| ▸ | HSD11B2 | P80365 | 5/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE6D | O43924 | 1/20 | 0.33 |
| ▸ | PDE6A | P16499 | 1/20 | 0.33 |
| ▸ | PDE6G | P18545 | 1/20 | 0.33 |
| ▸ | PDE6B | P35913 | 1/20 | 0.33 |
| ▸ | PDE6C | P51160 | 1/20 | 0.33 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978100 | 0.93 | HSD11B1 (0.33) | HSD11B1HSD11B2 | |
| SCHEMBL7977941 | 0.93 | HSD11B1 (0.35) | HSD11B1HSD11B2P2RX7 | |
| SCHEMBL7982916 | 0.88 | HSD11B2 (0.36) | HSD11B1HSD11B2P2RX7PDE2APDE6D | |
| SCHEMBL7968275 | 0.88 | HSD11B2 (0.39) | HSD11B1HSD11B2P2RX7 | |
| SCHEMBL7982078 | 0.86 | HSD11B1 (0.38) | HSD11B1HSD11B2 | |
| SCHEMBL12671332 | 0.86 | HSD11B1 (0.36) | HSD11B1P2RX7PDE2APDE6DPDE6A | |
| SCHEMBL12677376 | 0.86 | HSD11B1 (0.50) | HSD11B1HSD11B2PDE2APDE6DPDE6A | |
| SCHEMBL7992171 | 0.84 | CYP11B1 (0.35) | — | |
| SCHEMBL7981581 | 0.83 | HSD11B2 (0.38) | HSD11B1HSD11B2P2RX7 | |
| SCHEMBL7984202 | 0.82 | OPRM1 (0.36) | HSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |