Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 20/20 | 0.52 |
| ▸ | HRH1 | P35367 | 20/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978323 | 0.87 | HRH2 (0.54) | HRH2HRH1HRH3 | |
| SCHEMBL7980024 | 0.86 | HRH2 (0.51) | HRH2HRH1HRH3 | |
| SCHEMBL7978201 | 0.80 | HRH2 (0.58) | HRH2HRH1 | |
| SCHEMBL7976458 | 0.71 | HRH2 (0.67) | HRH2HRH1HRH3 | |
| SCHEMBL4496754 | 0.70 | LTA4H (0.44) | HRH3 | |
| SCHEMBL7442447 | 0.70 | MEN1 (0.46) | HRH3 | |
| SCHEMBL25533781 | 0.69 | HRH2 (0.60) | HRH2HRH1 | |
| SCHEMBL7245974 | 0.69 | HRH2 (1.00) | HRH2HRH1 | |
| SCHEMBL7246320 | 0.69 | HRH2 (1.00) | HRH2HRH1 | |
| SCHEMBL12251995 | 0.68 | HRH2 (0.52) | HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066534-A2 | CYCLIC AND BICYCLIC DIAMINO HISTAMINE-3 RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2001-09-13 | — | — | WO | claimed |