SCHEMBL7978227

SCHEMBL7978227

CCN(S)C(=O)Nc1nccs1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PKM P14618 3/20 0.55
SMN1; SMN2 Q16637 3/20 0.55
ALDH1A1 P00352 2/20 0.55
NPC1 O15118 3/20 0.51
RAB9A P51151 3/20 0.51
HTT P42858 3/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
PPARG P37231 1/20 0.51
NCOR2 Q9Y618 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
HIF1A Q16665 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
CDK5 Q00535 1/20 0.49
CDK5R1 Q15078 1/20 0.49
LMNA P02545 1/20 0.49
MAPT P10636 1/20 0.49
ACP1 P24666 1/20 0.49
ADORA2A P29274 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7130168 0.89 SMN1; SMN2 (0.55) PKMSMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL17186361 0.80 RAB9A (0.57) PKMSMN1; SMN2ALDH1A1NPC1RAB9A
Hydrochloric Acid SCHEMBL18605177 0.78 RAB9A (0.55) PKMSMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL175217 0.76 ADORA2A (0.68) PKMSMN1; SMN2ALDH1A1NPC1RAB9A
Bromide SCHEMBL27891199 0.75 ADORA2A (0.67) PKMSMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL11412643 0.74 RAB9A (0.57) SMN1; SMN2ALDH1A1NPC1RAB9AMEN1
SCHEMBL3430425 0.73 SMN1; SMN2 (0.77) PKMSMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL4112093 0.73 ADORA2A (0.70) PKMSMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL115951 0.73
SCHEMBL6755340 0.73 MAPT (0.54) SMN1; SMN2ALDH1A1NPC1RAB9AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6280917-B1 POLYMER HAVING AN ETHYLENICALLY UNSATURATED MONOMER UNIT CONTAINING AN ACTIVE METHYLENE GROUP AND AN ETHYLENICALLY UNSATURATED MONOMER UNIT SELECTED FROM METHACRYLIC ACID ESTER, ACRYLIC ACID ESTER, MALEIC ACID ESTER AND DIENE DERIVATIVE KONICA CORPORATION (JP) 2001-08-28 US disclosed
US-6093527-A INCREASE IN SENSITIVITY WHILE MAINTAINING LOW FOG AND EXCELLENT STORAGE STABILITY AT HIGH TEMPERATURE AND HUMIDITY; SPECTRALLY SENSITIZE A SHORT WAVELENGTH REGION OF 530 TO 540 NM OF GREEN LIGHT KONICA CORPORATION (JP) 2000-07-25 US disclosed
EP-0784228-B1 Silver halide grain, silver halide emulsion and preparation method thereof KONISHIROKU PHOTO IND (JP) 2000-05-24 EP disclosed
US-5851750-A Silver halide grain, silver halide emulsion and preparation method thereof KONICA CORPORATION (JP) 1998-12-22 US disclosed
EP-0784228-A1 Silver halide grain, silver halide emulsion and preparation method thereof KONICA CORPORATION (JP) 1997-07-16 EP disclosed