Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | CDK2 | P24941 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | METAP2 | P50579 | 1/20 | 0.52 |
| ▸ | METAP1 | P53582 | 1/20 | 0.52 |
| ▸ | SCD | O00767 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27737305 | 0.85 | RAB9A (0.60) | RAB9ANPC1AURKAPIM1CDK2 | |
| SCHEMBL3434055 | 0.78 | RAB9A (0.52) | RAB9ANPC1AURKAPIM1CDK2 | |
| SCHEMBL5810260 | 0.78 | NPC1 (0.52) | RAB9ANPC1AURKAPIM1CDK2 | |
| SCHEMBL7978227 | 0.74 | PKM (0.55) | RAB9ANPC1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL2634981 | 0.74 | RAB9A (0.56) | RAB9ANPC1PIM1CYP1A2SMN1; SMN2 | |
| SCHEMBL995829 | 0.73 | NPC1 (1.00) | RAB9ANPC1AURKAPIM1CDK2 | |
| SCHEMBL17186361 | 0.73 | RAB9A (0.57) | RAB9ANPC1AURKAPIM1CDK2 | |
| SCHEMBL9756407 | 0.72 | KMT2A (0.56) | RAB9ANPC1AURKAPIM1CDK2 | |
| SCHEMBL5353973 | 0.72 | MEN1 (0.56) | RAB9ANPC1SMN1; SMN2KMT2ATP53 | |
| Hydrochloric Acid SCHEMBL27594584 | 0.72 | NPC1 (0.97) | RAB9ANPC1AURKAPIM1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4200650-A | ENZYME INHIBITORS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1980-04-29 | — | — | US | disclosed |
| US-4199598-A | USE OF 2-AMINO-CYCLOPENT-1-ENE-1-DITHIOCARBOXYLIC ACIDS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1980-04-22 | — | — | US | disclosed |
| US-4179467-A | Dopamine hydroxylase inhibiting 2-amino-cyclopent-1-ene-1-thiocarboxylic acid-disulfides | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1979-12-18 | — | — | US | disclosed |
| US-4179463-A | ADRENERGIC BLOCKING AGENTS, DOPAMINE-B-HYDROXYLASE INHIBITORS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1979-12-18 | — | — | US | disclosed |