Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | P4HB | P07237 | 2/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9183668 | 0.81 | MAPT (0.44) | ALDH1A1MAPTL3MBTL1HTTKMT2A | |
| SCHEMBL24740469 | 0.73 | FBP1 (0.47) | ALDH1A1MAPTLMNAL3MBTL1FBP1 | |
| SCHEMBL19732122 | 0.73 | HCAR2 (0.46) | ALDH1A1MAPTLMNACES2CES1 | |
| SCHEMBL9163004 | 0.70 | CYP19A1 (0.39) | ALDH1A1MAPTLMNAPGRKMT2A | |
| SCHEMBL28485840 | 0.69 | HDAC2 (0.51) | ALDH1A1MAPTLMNAL3MBTL1FBP1 | |
| SCHEMBL880407 | 0.68 | MAPT (0.68) | ALDH1A1MAPTLMNAL3MBTL1HDAC2 | |
| SCHEMBL9412024 | 0.67 | PGR (0.48) | ALDH1A1MAPTLMNAL3MBTL1FBP1 | |
| SCHEMBL9412021 | 0.67 | PGR (0.48) | ALDH1A1MAPTLMNAL3MBTL1FBP1 | |
| SCHEMBL8699093 | 0.67 | FBP1 (0.59) | ALDH1A1MAPTLMNAL3MBTL1FBP1 | |
| SCHEMBL1687898 | 0.67 | FBP1 (0.59) | ALDH1A1MAPTLMNAL3MBTL1FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239280-B1 | OXIDATION THE CORRESPONSING THIOIMIDAZOLE COMPOUND | MERCK & CO., INC. | 2001-05-29 | — | — | US | disclosed |