Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2619347 | 0.98 | NFKB1 (0.54) | NFKB1L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL31190152 | 0.92 | RAB9A (0.51) | NFKB1L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL11575820 | 0.91 | RAB9A (0.54) | NFKB1L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL24081206 | 0.86 | NFKB1 (0.54) | NFKB1L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL662136 | 0.86 | HRH3 (0.46) | NFKB1L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL20411973 | 0.85 | NFKB1 (0.53) | NFKB1L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL10459617 | 0.84 | RARB (0.47) | NFKB1L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL20415539 | 0.83 | HRH3 (0.41) | NFKB1L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL6502585 | 0.83 | NFKB1 (0.56) | NFKB1L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL7523389 | 0.83 | NFKB1 (0.51) | NFKB1L3MBTL1MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277851-B1 | ORALLY ADMINISTERED TRYPSIN-RELATED SERINE PROTEASE INHIBITORS; ANTICOAGULANTS | ADIR ET COMPAGNIE (FR) | 2001-08-21 | — | — | US | disclosed |