SCHEMBL7978481

SCHEMBL7978481

CC[C@@H](C)[C@@H](Br)C(=O)NC1(C(=O)NC(Cc2ccc3c(c2)oc2ccccc23)C(=O)OC)CCCC1

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 11/20 0.43
MME P08473 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
TACR2 P21452 6/20 0.38
KDR P35968 1/20 0.36
PTGS2 P35354 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7978479 1.00 ECE1 (0.43) ECE1MMEMEN1KMT2ATACR2
SCHEMBL7962587 0.83 ECE1 (0.54) ECE1MME
SCHEMBL7962528 0.83 ECE1 (0.54) ECE1MME
SCHEMBL7972340 0.81 ECE1 (0.44) ECE1MMEMEN1KMT2AKDR
SCHEMBL7976231 0.79 ECE1 (0.49) ECE1MMEMEN1KMT2AKDR
SCHEMBL7973783 0.78 ECE1 (0.63) ECE1MMEMEN1KMT2A
SCHEMBL7973787 0.78 ECE1 (0.63) ECE1MMEMEN1KMT2A
Hydrochloric Acid SCHEMBL7976234 0.78 ECE1 (0.48) ECE1MMEMEN1KMT2AKDR
Hydrochloric Acid SCHEMBL7976229 0.78 ECE1 (0.48) ECE1MMEMEN1KMT2AKDR
SCHEMBL7975857 0.77 ECE1 (0.57) ECE1MMEMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001077095-A2 DERIVATIVES OF ALPHA-MERCAPTOACETAMIDE NOVARTIS AG (CH) 2001-10-18 WO disclosed