Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 11/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7976234 | 0.99 | ECE1 (0.48) | ECE1KMT2AMMEMEN1LCK | |
| Hydrochloric Acid SCHEMBL7976229 | 0.99 | ECE1 (0.48) | ECE1KMT2AMMEMEN1LCK | |
| SCHEMBL7975670 | 0.84 | ECE1 (0.55) | ECE1KMT2AMMEMEN1LCK | |
| SCHEMBL7972405 | 0.84 | ECE1 (0.55) | ECE1KMT2AMMEMEN1LCK | |
| SCHEMBL7972340 | 0.81 | ECE1 (0.44) | ECE1KMT2AMMEMEN1LCK | |
| SCHEMBL7962457 | 0.79 | KLK5 (0.53) | ECE1KMT2AMMEMEN1KDR | |
| SCHEMBL7962462 | 0.79 | KLK5 (0.53) | ECE1KMT2AMMEMEN1KDR | |
| SCHEMBL13779399 | 0.79 | LCK (0.66) | KMT2ALCKATMNPSR1MDM4 | |
| SCHEMBL7978479 | 0.79 | ECE1 (0.43) | ECE1KMT2AMMEMEN1KDR | |
| SCHEMBL7978481 | 0.79 | ECE1 (0.43) | ECE1KMT2AMMEMEN1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001077095-A2 | DERIVATIVES OF ALPHA-MERCAPTOACETAMIDE | NOVARTIS AG (CH) | 2001-10-18 | — | — | WO | disclosed |