Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | TOP2A | P11388 | 6/20 | 0.52 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3549628 | 0.96 | STAT3 (0.63) | STAT3ADRB2TOP2ATOP2BKCNH2 | |
| SCHEMBL30891255 | 0.89 | TOP2A (0.60) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| SCHEMBL6659404 | 0.89 | TOP2A (0.60) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| SCHEMBL30863948 | 0.87 | STAT3 (0.56) | STAT3ADRB2TOP2ATOP2BKCNH2 | |
| SCHEMBL5704368 | 0.87 | STAT3 (0.56) | STAT3ADRB2TOP2ATOP2BKCNH2 | |
| SCHEMBL9186289 | 0.87 | ADRB2 (0.59) | STAT3ADRB2TOP2ATOP2BKCNH2 | |
| SCHEMBL29492858 | 0.85 | ADRB2 (0.68) | STAT3ADRB2TOP2ATOP2BKCNH2 | |
| SCHEMBL2844967 | 0.85 | ADRB2 (0.68) | STAT3ADRB2TOP2ATOP2BKCNH2 | |
| SCHEMBL2670429 | 0.85 | STAT3 (0.61) | STAT3ADRB2ALDH1A1 | |
| SCHEMBL3551375 | 0.85 | STAT3 (0.61) | STAT3ADRB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323213-B1 | ANTIBIOTICS, BACTERICIDES FOR VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 2001-11-27 | — | — | US | disclosed |