Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 7/20 | 0.60 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CLK2 | P49760 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30891255 | 1.00 | TOP2A (0.60) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL7978648 | 0.89 | STAT3 (0.59) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL966067 | 0.89 | ALDH1A1 (0.57) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL30468815 | 0.89 | ALDH1A1 (0.57) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL13470136 | 0.89 | TOP2A (0.58) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL8339253 | 0.88 | TOP2A (0.60) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL13341758 | 0.86 | TOP2A (0.45) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL6659405 | 0.85 | TOP2A (0.44) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL500719 | 0.85 | TOP2A (0.71) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL29463823 | 0.85 | TOP2A (0.71) | TOP2ATOP2BALDH1A1POLBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111989314-B | Method for hydrolyzing quinolone formate | 拜耳动物保健有限责任公司 | 2024-04-30 | — | — | CN | claimed |
| EP-3784656-B1 | PROCESS FOR THE HYDROLYSIS OF QUINOLONE CARBOXYLIC ESTERS | ELANCO ANIMAL HEALTH GMBH (DE) | 2023-06-28 | — | — | EP | claimed |
| US-11332444-B2 | Method for the hydrolysis of quinolonecarboxylic esters | BAYER ANIMAL HEALTH GMBH (DE) | 2022-05-17 | — | — | US | claimed |
| US-20210078950-A1 | METHOD FOR THE HYDROLYSIS OF QUINOLONECARBOXYLIC ESTERS | ELANCO ANIMAL HEALTH GMBH (DE) | 2021-03-18 | — | — | US | claimed |
| EP-3784656-A1 | PROCESS FOR THE HYDROLYSIS OF QUINOLONE CARBOXYLIC ESTERS | Bayer Animal Health GmbH (DE) | 2021-03-03 | — | — | EP | claimed |
| CN-111989314-A | Process for hydrolysis of quinolone formates | 拜耳动物保健有限责任公司 | 2020-11-24 | — | — | CN | claimed |
| EP-1236718-B1 | Improved process for the preparation of fluoro-quinolonecarboxylic acids | BAYER CHEMICALS AG (DE) | 2004-08-11 | — | — | EP | claimed |
| US-6590101-B2 | Hydrolysis of the corresponding C1-C4-alkyl esters with addition of water, acetic acid, and sulfuric acid using a drastically reduced amount of sulfuric acid | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-08 | — | — | US | claimed |
| EP-1236718-A1 | Improved process for the preparation of fluoro-quinolonecarboxylic acids | BAYER AG (DE) | 2002-09-04 | — | — | EP | claimed |
| US-20020120138-A1 | Process for the preparation of fluoroquinolonecarboxylic acids | LANXESS DEUTSCHLAND GMBH (DE) | 2002-08-29 | — | — | US | claimed |
| CN-111989314-B | Method for hydrolyzing quinolone formate | 拜耳动物保健有限责任公司 | 2024-04-30 | — | — | CN | disclosed |
| EP-3784656-B1 | PROCESS FOR THE HYDROLYSIS OF QUINOLONE CARBOXYLIC ESTERS | ELANCO ANIMAL HEALTH GMBH (DE) | 2023-06-28 | — | — | EP | disclosed |
| US-11332444-B2 | Method for the hydrolysis of quinolonecarboxylic esters | BAYER ANIMAL HEALTH GMBH (DE) | 2022-05-17 | — | — | US | disclosed |
| US-20210078950-A1 | METHOD FOR THE HYDROLYSIS OF QUINOLONECARBOXYLIC ESTERS | ELANCO ANIMAL HEALTH GMBH (DE) | 2021-03-18 | — | — | US | disclosed |
| EP-3784656-A1 | PROCESS FOR THE HYDROLYSIS OF QUINOLONE CARBOXYLIC ESTERS | Bayer Animal Health GmbH (DE) | 2021-03-03 | — | — | EP | disclosed |
| US-20020120138-A1 | Process for the preparation of fluoroquinolonecarboxylic acids | LANXESS DEUTSCHLAND GMBH (DE) | 2002-08-29 | — | — | US | disclosed |
| EP-1215202-A1 | Intermediates for the preparation of possibly substituted 8-cyano-1-cyclopropyl-7-(2,8-diazabicyclo-(4.3.0)-nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolin carboxylic acids and their derivatives | BAYER AG (DE) | 2002-06-19 | — | — | EP | disclosed |
| US-6278013-B1 | AS CHEMICAL INTERMEDIATES FOR PREPARING QUINOLINECARBOXYLIC ACID DERIVATIVE ANTIBIOTICS USED IN VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-21 | — | — | US | disclosed |
| EP-1001929-A1 | METHOD FOR PREPARING 3-CYANO-2,4-DIHALOGEN-5-FLUOR-BENZOIC ACID | Bayer Aktiengesellschaft (DE) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999006360-A1 | METHOD FOR PREPARING 3-CYANO-2,4-DIHALOGEN-5-FLUOR-BENZOIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020120138-A1 | Process for the preparation of fluoroquinolonecarboxylic acids | ADH1C, CTRC, ADH1A | TOP2A 352/4885TOP2B 365/4885ALDH1A1 124/4885 |
| US-20210078950-A1 | METHOD FOR THE HYDROLYSIS OF QUINOLONECARBOXYLIC ESTERS | NQO2, PGD, ALAD | TOP2A 38/4885TOP2B 35/4885ALDH1A1 274/4885 |
| US-11332444-B2 | Method for the hydrolysis of quinolonecarboxylic esters | NQO2, PGD, ALAD | TOP2A 38/4885TOP2B 35/4885ALDH1A1 274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.