Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 20/20 | 0.77 |
| ▸ | MMP13 | P45452 | 20/20 | 0.77 |
| ▸ | MMP2 | P08253 | 1/20 | 0.77 |
| ▸ | MMP3 | P08254 | 1/20 | 0.77 |
| ▸ | MMP9 | P14780 | 1/20 | 0.77 |
| ▸ | MMP8 | P22894 | 1/20 | 0.77 |
| ▸ | MMP12 | P39900 | 1/20 | 0.77 |
| ▸ | MMP14 | P50281 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2575324 | 0.89 | MMP1 (0.79) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL25304 | 0.87 | MMP1 (1.00) | MMP1MMP13MMP2MMP3MMP9 | |
| Hydroxyamine SCHEMBL5914587 | 0.87 | MMP1 (0.76) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL5914586 | 0.86 | MMP1 (0.74) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7208011 | 0.85 | MMP1 (0.80) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL1080224 | 0.85 | MMP1 (0.80) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL12076481 | 0.85 | MMP1 (0.80) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6946064 | 0.83 | MMP1 (0.70) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL135680 | 0.83 | MMP1 (1.00) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7208581 | 0.83 | MMP1 (0.77) | MMP1MMP13MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288246-B1 | REACTION OF HYDROXYLAMINE WITH ALKYLSILYL HALIDE, HYDROLYSIS WITH ACID | PFIZER INC | 2001-09-11 | — | — | US | disclosed |
| EP-0949244-A2 | Process for preparing hydroxamic acids | Pfizer Products Inc. (US) | 1999-10-13 | — | — | EP | disclosed |