Hydroxyamine

Hydroxyamine

SCHEMBL5914587

NO.O=C(O)C1(NS(=O)(=O)c2ccc(Oc3ccc(F)cc3)cc2)CCOCC1

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 20/20 0.76
MMP13 P45452 20/20 0.76
MMP2 P08253 1/20 0.76
MMP3 P08254 1/20 0.76
MMP9 P14780 1/20 0.76
MMP8 P22894 1/20 0.76
MMP12 P39900 1/20 0.76
MMP14 P50281 1/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2575324 0.98 MMP1 (0.79) MMP1MMP13MMP2MMP3MMP9
Hydroxyamine SCHEMBL5139159 0.93 MMP1 (0.77) MMP1MMP13MMP2MMP3MMP9
SCHEMBL1080224 0.91 MMP1 (0.80) MMP1MMP13MMP2MMP3MMP9
SCHEMBL12076481 0.91 MMP1 (0.80) MMP1MMP13MMP2MMP3MMP9
SCHEMBL7208011 0.91 MMP1 (0.80) MMP1MMP13MMP2MMP3MMP9
SCHEMBL27415619 0.89 MMP1 (0.76) MMP1MMP13MMP2MMP3MMP9
Hydroxyamine SCHEMBL7514521 0.88 MMP1 (0.76) MMP1MMP13MMP2MMP3MMP9
SCHEMBL5914586 0.87 MMP1 (0.74) MMP1MMP13MMP2MMP3MMP9
SCHEMBL7978660 0.87 MMP1 (0.77) MMP1MMP13MMP2MMP3MMP9
SCHEMBL6869740 0.87 MMP1 (0.77) MMP1MMP13MMP2MMP3MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2796468-A2 Antibodies to insulin-like growth factor I receptor Pfizer Inc (US) 2014-10-29 EP disclosed
US-20060165636-A1 Hair treatment composition and hair cosmetic for damaged hair MEIJI SEIKA KAISHA, LTD. (JP) 2006-07-27 US disclosed
US-20060128724-A1 Pyrazole-substituted aminoheteroaryl compounds as protein kinase inhibitors AGOURON PHARMACEUTICALS, INC. 2006-06-15 US disclosed
EP-1602354-A1 HAIR TREATMENT COMPOSITION AND HAIR COSMETIC FOR DAMAGED HAIR Meiji Seika Kaisha, Ltd. (JP) 2005-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060128724-A1 Pyrazole-substituted aminoheteroaryl compounds as protein kinase inhibitors MET, MAP3K15, MAP3K19 MMP1 4431/4885MMP13 4056/4885MMP2 3651/4885
US-20060165636-A1 Hair treatment composition and hair cosmetic for damaged hair CUTA, COL14A1, PRKDC MMP1 397/4885MMP13 203/4885MMP2 1163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.