Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.39 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9914978 | 0.86 | POLB (0.55) | CA2CA12CA1CA9DPP4 | |
| Hydrochloric Acid SCHEMBL25327489 | 0.84 | POLB (0.53) | CA2CA12CA1CA9DPP4 | |
| SCHEMBL12582875 | 0.81 | ATM (0.48) | POLBNPSR1L3MBTL1GAA | |
| SCHEMBL8487735 | 0.81 | ATM (0.48) | POLBNPSR1L3MBTL1GAA | |
| SCHEMBL13761296 | 0.81 | POLB (0.42) | CA2CA12CA1CA9DPP4 | |
| SCHEMBL19757974 | 0.79 | POLB (0.49) | CA2DPP4CHKAPOLBNPSR1 | |
| SCHEMBL8488279 | 0.79 | MEN1 (0.47) | POLBNPSR1L3MBTL1GAA | |
| SCHEMBL12583677 | 0.78 | HTR1A (0.47) | POLBNPSR1L3MBTL1CACNA2D1CACNA1B | |
| SCHEMBL12583610 | 0.78 | HTR1A (0.47) | POLBNPSR1L3MBTL1CACNA2D1CACNA1B | |
| SCHEMBL13383340 | 0.78 | HTR1A (0.47) | POLBNPSR1L3MBTL1CACNA2D1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313294-B1 | Process for preparing amides | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2001-11-06 | — | — | US | disclosed |
| EP-0225866-B1 | QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE | Gerot-Pharmazeutika Gesellschaft m.b.H. (AT) | 1991-09-25 | — | — | EP | disclosed |
| US-4795750-A | HYPOTENSIVE AGENTS | GEROT-PHARMAZEUTIKA GESELLSCHAFT (AT) | 1989-01-03 | — | — | US | disclosed |
| EP-0225866-A2 | Quinazoline derivatives, process for their preparation, pharmaceutical compositions containing them and their use | Gerot-Pharmazeutika Gesellschaft m.b.H. (AT) | 1987-06-16 | — | — | EP | disclosed |