SCHEMBL8488279

SCHEMBL8488279

CC(O)CC(=O)N1CCCCC1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
TDP1 Q9NUW8 1/20 0.47
ATM Q13315 1/20 0.46
GAA P10253 1/20 0.43
POLB P06746 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
ALDH1A1 P00352 2/20 0.42
NPC1 O15118 1/20 0.42
HPGD P15428 1/20 0.42
HTT P42858 1/20 0.42
BCHE P06276 1/20 0.41
ACHE P22303 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8487735 0.98 ATM (0.48) MEN1KMT2AL3MBTL1TDP1ATM
SCHEMBL12582875 0.98 ATM (0.48) MEN1KMT2AL3MBTL1TDP1ATM
SCHEMBL8250570 0.84 POLB (0.58) MEN1KMT2AL3MBTL1TDP1ATM
SCHEMBL3740475 0.84 POLB (0.58) MEN1KMT2AL3MBTL1TDP1ATM
SCHEMBL8488275 0.83 L3MBTL1 (0.47) MEN1KMT2AL3MBTL1TDP1ATM
SCHEMBL7223652 0.82 POLB (0.60) MEN1KMT2AL3MBTL1TDP1ATM
SCHEMBL11844764 0.81 L3MBTL1 (0.46) MEN1KMT2AL3MBTL1TDP1ATM
SCHEMBL13383340 0.81 HTR1A (0.47) KMT2AL3MBTL1TDP1POLBNPSR1
SCHEMBL8488655 0.81 MEN1 (0.46) MEN1KMT2AL3MBTL1TDP1ATM
SCHEMBL12583610 0.81 HTR1A (0.47) KMT2AL3MBTL1TDP1POLBNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6184144-A None JP disclosed
US-5958837-A 2-(PHENYLMETHOXY OR CARBONYLOXY-(1,4-PHENYLENE)-),3-HALO,5-HALOALKYLPYRIDINES; HERBICIDES EFFECTING DESICCATION AND DEFOLIATION OF PLANTS; GOOD ACTIVITY AND BETTER TAILORED CONTROL OF WEEDS BASF AKTIENGESELLSCHAFT (DE) 1999-09-28 US disclosed
EP-0802904-B1 SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES BASF AG (DE) 1998-09-09 EP disclosed
EP-0802904-A1 SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1997-10-29 EP disclosed
US-5391761-A Used as mnemotonic, antiparkinsonian, antidepressive and antipsychiatric agent CENTRE D'ETUDES EXPERIMENTALS ET CLINIQUES DE PHARMACOLOGIE ET D'EUTONOLOGIE (CEPBEPE) (FR) 1995-02-21 US disclosed
JP-H06184144-A CYCLIC DERIVATIVE AND REMEDIES FOR NEUROLOGICAL AND PSYCHIOTRIC DISORDERS CENTRE ETUD EXPERIMENT & CLINIQUES DE PHYSIO BIOLOG DE PHARMACOLOG & EUTONOLOG 1994-07-05 JP disclosed
EP-0578560-A2 Amido-alcohol derivatives as psychotropic agents CENTRE D'ETUDES EXPERIMENTALES ET CLINIQUES DE PHYSIO-BIOLOGIE, DE PHARMACOLOGIE ET D'EUTONOLOGIE (CEPBEPE) (FR) 1994-01-12 EP disclosed