SCHEMBL7979241

SCHEMBL7979241

O=C(CCCNc1ccc(C(F)(F)F)cc1F)Oc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.37
HTT P42858 4/20 0.37
GAA P10253 2/20 0.37
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
LMNA P02545 2/20 0.34
F10 P00742 1/20 0.33
HDAC1 Q13547 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MGLL Q99685 2/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
BRAF P15056 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7979399 0.91 MAPT (0.34) MAPTHTTGAAMEN1KMT2A
SCHEMBL7976379 0.91 HDAC1 (0.39) MAPTMEN1KMT2AHDAC1HDAC8
SCHEMBL7977810 0.89 NPSR1 (0.34) MAPTHTTMEN1KMT2ALMNA
SCHEMBL7965920 0.87 MAPT (0.50) MAPTHTTGAAMEN1KMT2A
SCHEMBL7979279 0.87 MAPT (0.36) MAPTHTTGAAMEN1KMT2A
SCHEMBL7979244 0.86 GAA (0.38) MAPTHTTGAAHDAC1CYP11B1
SCHEMBL7976381 0.82 HDAC1 (0.42) MAPTHTTGAALMNAHDAC1
SCHEMBL7982370 0.81 MAPT (0.37) MAPTHTTGAALMNAALDH1A1
SCHEMBL7979400 0.81 FLT1 (0.37) MAPTHTTGAAMEN1KMT2A
SCHEMBL7977672 0.80 TDP1 (0.38) MAPTHTTGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6214835-B1 CONTROLLING INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-04-10 US disclosed