SCHEMBL7977810

SCHEMBL7977810

O=C(CCCNc1ccc(Cl)cc1F)Oc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
HIF1A Q16665 1/20 0.34
NR4A2 P43354 1/20 0.34
HTT P42858 1/20 0.33
MAPT P10636 4/20 0.33
ALDH1A1 P00352 3/20 0.33
KMT2A Q03164 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
POLB P06746 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
MPI P34949 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
GCGR P47871 2/20 0.31
TRPM5 Q9NZQ8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7977672 0.89 TDP1 (0.38) SMN1; SMN2CYP1A2CYP2C9HIF1ANR4A2
SCHEMBL7979241 0.89 MAPT (0.37) SMN1; SMN2CYP1A2HTTMAPTALDH1A1
SCHEMBL7965903 0.86 TRPM5 (0.34) NPSR1SMN1; SMN2HTTMAPTALDH1A1
SCHEMBL7977813 0.85 FOLH1 (0.40) MAPTALDH1A1KMT2AL3MBTL1POLB
SCHEMBL7979399 0.81 MAPT (0.34) SMN1; SMN2CYP1A2HTTMAPTALDH1A1
SCHEMBL7976379 0.81 HDAC1 (0.39) NPSR1SMN1; SMN2CYP1A2CYP2C9MAPT
SCHEMBL7975943 0.80 NPSR1 (0.35) NPSR1SMN1; SMN2HTTMAPTALDH1A1
SCHEMBL7977673 0.80 KMT2A (0.45) NPSR1CYP1A2HTTMAPTALDH1A1
SCHEMBL7965920 0.78 MAPT (0.50) SMN1; SMN2CYP1A2CYP2C9HTTMAPT
SCHEMBL7979244 0.75 GAA (0.38) HTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6214835-B1 CONTROLLING INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-04-10 US disclosed