Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 7/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 4/20 | 0.44 |
| ▸ | HTR2C | P28335 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473671 | 0.84 | ADRA1D (0.59) | ADRA1DADRA1AADRA1BADRA2AADRA2B | |
| SCHEMBL7684701 | 0.84 | ADRA1D (0.70) | ADRA1DADRA1AADRA1BADRA2AADRA2B | |
| SCHEMBL7681671 | 0.84 | ADRA1D (0.70) | ADRA1DADRA1AADRA1BADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL8130944 | 0.84 | ADRA1D (0.58) | ADRA1DADRA1AADRA1BADRA2AADRA2B | |
| SCHEMBL7684198 | 0.83 | ADRA1D (0.49) | ADRA1DADRA1AADRA1BADRA2AADRA2B | |
| SCHEMBL7466853 | 0.82 | ADRA1D (0.66) | ADRA1DADRA1AADRA1BADRA2AADRA2B | |
| SCHEMBL7684155 | 0.82 | ADRA1A (0.47) | ADRA1DADRA1AADRA1BADRA2AADRA2B | |
| SCHEMBL7474546 | 0.82 | ADRA1D (0.69) | ADRA1DADRA1AADRA1BADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL8117955 | 0.81 | ADRA1D (0.64) | ADRA1DADRA1AADRA1BADRA2AADRA2B | |
| SCHEMBL7467731 | 0.81 | ADRA1D (0.58) | ADRA1DADRA1AADRA1BADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201004-B1 | CENTRAL NERVOUS SYSTEM, PSYCHOLOGICAL, EATING, CARDIOVASCULAR, BRAIN, AND GASTROINTESTINAL DISORDERS | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-03-13 | — | — | US | disclosed |