Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979274 | 1.00 | L3MBTL1 (0.41) | L3MBTL1MAPTALDH1A1GAATSHR | |
| SCHEMBL7690672 | 0.94 | L3MBTL1 (0.38) | L3MBTL1MAPTALDH1A1GAATSHR | |
| SCHEMBL7690671 | 0.94 | L3MBTL1 (0.38) | L3MBTL1MAPTALDH1A1GAATSHR | |
| SCHEMBL7684170 | 0.92 | MAPT (0.42) | L3MBTL1MAPTALDH1A1TSHRNPSR1 | |
| SCHEMBL7684171 | 0.92 | MAPT (0.42) | L3MBTL1MAPTALDH1A1TSHRNPSR1 | |
| SCHEMBL7690667 | 0.89 | MAPT (0.39) | L3MBTL1MAPTALDH1A1TSHRNPSR1 | |
| SCHEMBL7684749 | 0.89 | MAPT (0.39) | L3MBTL1MAPTALDH1A1NPSR1TP53 | |
| SCHEMBL7684744 | 0.89 | MAPT (0.39) | L3MBTL1MAPTALDH1A1NPSR1TP53 | |
| SCHEMBL7690669 | 0.89 | MAPT (0.39) | L3MBTL1MAPTALDH1A1TSHRNPSR1 | |
| SCHEMBL7977662 | 0.88 | L3MBTL1 (0.39) | L3MBTL1MAPTALDH1A1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303783-B1 | 1- (3-Heterocyclylphenyl) isothiourea, -isourea, -guanidine and -amidine herbicidal agents | AMERICAN CYANAMID CO. | 2001-10-16 | — | — | US | disclosed |
| EP-0985670-A1 | 1-(3-Heterocyclylphenyl)isothiourea, -isourea, -guanidine and -amidine compounds as herbicides | American Cyanamid Company (US) | 2000-03-15 | — | — | EP | disclosed |