Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27570466 | 0.90 | PTGS2 (0.41) | PTGS2PTGS1NR3C1PGRNR3C2 | |
| SCHEMBL6742689 | 0.89 | PTGS2 (0.47) | PTGS2PTGS1NR3C1PGRNR3C2 | |
| SCHEMBL6740283 | 0.88 | PTGS2 (0.49) | PTGS2PTGS1NR3C1PGRNR3C2 | |
| SCHEMBL6741606 | 0.85 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL6742555 | 0.82 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL6738511 | 0.76 | PTGS2 (0.48) | PTGS2PTGS1NR3C1PGRNR3C2 | |
| SCHEMBL27589146 | 0.76 | NR3C1 (0.43) | NR3C1PGRNR3C2 | |
| SCHEMBL27570465 | 0.74 | NR3C1 (0.36) | NR3C1PGRNR3C2 | |
| SCHEMBL21675747 | 0.71 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL27589143 | 0.70 | GRM2 (0.38) | PTGS2PTGS1NR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001090097-A2 | NOVEL COMPOUNDS HAVING ANTIINFLAMMATORY ACTIVITY: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2001-11-29 | — | — | WO | claimed |