SCHEMBL7979357

SCHEMBL7979357

CS(=O)(=O)Nc1cc(C(O)CBr)ccc1Br

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADRB3 P13945 17/20 0.55
ADRB2 P07550 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7979355 1.00 ADRB3 (0.55) ADRB3ADRB2
SCHEMBL12305628 0.85 ADRB3 (0.74) ADRB3ADRB2
SCHEMBL7110735 0.84 ADRB3 (0.53) ADRB3ADRB2
SCHEMBL7113249 0.84 ADRB3 (0.53) ADRB3ADRB2
SCHEMBL7113252 0.84 ADRB3 (0.53) ADRB3ADRB2
SCHEMBL7113209 0.84 ADRB3 (0.53) ADRB3ADRB2
SCHEMBL7113347 0.84 ADRB3 (0.53) ADRB3ADRB2
SCHEMBL7110732 0.84 ADRB3 (0.53) ADRB3ADRB2
SCHEMBL7108854 0.77 ALDH1A1 (0.51) ADRB3ADRB2
SCHEMBL14620533 0.77 ADRB3 (0.46) ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6172099-B1 CARBAZOLE, DIBENZOFURAN, OR DIBENZOTHIOPHENE DERIVATIVES; DIETETICS, ANTIDIABETIC AGENTS; ANTILIPEMICS ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2001-01-09 US disclosed
EP-0997458-A1 NOVEL TRICYCLIC COMPOUNDS HAVING SATURATED RINGS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-05-03 EP disclosed