Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 10/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973746 | 0.86 | NPY5R (0.44) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL7979596 | 0.85 | NPY5R (0.52) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL7963446 | 0.82 | MAPT (0.57) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL7977193 | 0.79 | NPSR1 (0.78) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL7974767 | 0.78 | NPY5R (0.54) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL7976798 | 0.78 | RORC (0.52) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL25179738 | 0.77 | NPSR1 (0.68) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL7977223 | 0.76 | NPY5R (0.53) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL30150496 | 0.73 | KDM4E (0.68) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL7979578 | 0.73 | KDM4E (0.68) | NPSR1MAPTKDM4ELMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | claimed |
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |