Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979243 | 0.89 | CACNB4 (0.38) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL7978016 | 0.84 | PLA2G2A (0.47) | POLBALDH1A1SMN1; SMN2LMNAPLA2G2A | |
| SCHEMBL8802602 | 0.79 | PTPN11 (0.36) | PTPN11 | |
| SCHEMBL13410042 | 0.78 | GAA (0.47) | POLBALDH1A1GAASLC6A3HTT | |
| SCHEMBL30587182 | 0.77 | SMN1; SMN2 (0.49) | POLBALDH1A1GAASLC6A3HTT | |
| SCHEMBL6951228 | 0.77 | SMN1; SMN2 (0.49) | POLBALDH1A1GAASLC6A3HTT | |
| SCHEMBL6949718 | 0.75 | GAA (0.56) | POLBALDH1A1GAASLC6A3HTT | |
| SCHEMBL30686655 | 0.75 | GAA (0.56) | POLBALDH1A1GAASLC6A3HTT | |
| SCHEMBL31231118 | 0.75 | GAA (0.56) | POLBALDH1A1GAASLC6A3HTT | |
| SCHEMBL7977566 | 0.74 | HTT (0.42) | POLBALDH1A1GAASLC6A3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194428-B1 | BRAIN DISORDERS; PSYCHOLOGICAL DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-27 | — | — | US | claimed |