Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 20/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979243 | 0.86 | CACNB4 (0.38) | PTPN11 | |
| SCHEMBL7979537 | 0.79 | POLB (0.44) | PTPN11 | |
| SCHEMBL8801316 | 0.76 | IMPDH2 (0.40) | — | |
| SCHEMBL8802499 | 0.76 | LMNA (0.44) | PTPN11 | |
| SCHEMBL10913637 | 0.75 | PTPN11 (0.39) | PTPN11 | |
| SCHEMBL7967602 | 0.71 | CACNB4 (0.39) | PTPN11 | |
| SCHEMBL7984061 | 0.71 | CACNB4 (0.42) | — | |
| SCHEMBL8803416 | 0.70 | SLC6A3 (0.38) | — | |
| SCHEMBL9537421 | 0.68 | TSHR (0.53) | — | |
| SCHEMBL10921719 | 0.68 | SMN1; SMN2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778769-A1 | USE OF 5-SUBSTITUTED PYRIDINE AND HEXAHYDROQUINOLINE-3 CARBOXYLIC ACID DERIVATIVES FOR TREATING DISEASES OF THE CENTRAL NERVOUS SYSTEM | BAYER AG (DE) | 1997-06-18 | — | — | EP | claimed |
| WO-1996006610-A1 | USE OF 5-SUBSTITUTED PYRIDINE AND HEXAHYDROQUINOLINE-3 CARBOXYLIC ACID DERIVATIVES FOR TREATING DISEASES OF THE CENTRAL NERVOUS SYSTEM | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-07 | — | — | WO | claimed |