Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3425174 | 0.78 | PDE5A (0.46) | KMT2APDE5APDE4APDE4BPDE4C | |
| SCHEMBL3433600 | 0.78 | SMN1; SMN2 (0.50) | KMT2APDE5APDE4APDE4BPDE4C | |
| SCHEMBL20969999 | 0.78 | SMN1; SMN2 (0.45) | KMT2APDE5APDE4APDE4BPDE4C | |
| SCHEMBL6358364 | 0.77 | KMT2A (0.41) | KMT2APDE5APDE4APDE4BPDE4C | |
| SCHEMBL7983821 | 0.76 | PDE4A (0.45) | KMT2APDE5APDE4APDE4BPDE4C | |
| SCHEMBL2776927 | 0.76 | SMN1; SMN2 (0.46) | KMT2APDE5APDE4APDE4BPDE4C | |
| SCHEMBL6550714 | 0.75 | LMNA (0.52) | ALDH1A1CFTRGAASMN1; SMN2TLR7 | |
| SCHEMBL6800743 | 0.72 | LMNA (0.48) | POLBCFTRGAASMN1; SMN2MAPT | |
| SCHEMBL6550804 | 0.72 | LMNA (0.48) | POLBCFTRGAASMN1; SMN2MAPT | |
| SCHEMBL1573111 | 0.71 | PDE5A (0.51) | KMT2APDE5APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001096339-A1 | NOVEL TELOMERASE INHIBITORS | PHARMACIA ITALIA S.P.A. (IT) | 2001-12-20 | — | — | WO | disclosed |